Synthesis and Characterization of 4-[(3,5-Dimethyl-1H-pyrazol-1-yl)Methyl]-4-Methyl-2-Phenyl-4,5-Dihydrooxazole
Theory and Applications of Chemistry Vol. 4,
Page 109-115
Abstract
The compound, 4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-4-methyl-2-phenyl-4,5-dihydrooxazole 2 was prepared in high yield, through nucleophilic substitution reaction of the O-tosyloxazoline derivative 1, by heating in dimethyl sulfoxide (DMSO) and in presence of KOH as base. The structure of the synthesized compound was established on the basis of NMR spectroscopy (1H, 13C), MS data and elemental analysis.
Keywords:
- Oxazoline
- pyrazole
- N-alkylation
- 2D NMR
How to Cite
Hajib, S., Aouine, Y., Alami, A., Faraj, H., & Hallaoui, A. E. (2020). Synthesis and Characterization of 4-[(3,5-Dimethyl-1H-pyrazol-1-yl)Methyl]-4-Methyl-2-Phenyl-4,5-Dihydrooxazole. Theory and Applications of Chemistry Vol. 4, 109-115. Retrieved from https://stm1.bookpi.org/index.php/tac-v4/article/view/1105
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