Diaplant-Neo: Complex Therapy of Acute Intestinal Infections
Trends in Pharmaceutical Research and Development Vol. 2,
Page 145-153
Abstract
Aims: To develop the composition and technology of the combined capsules "Diaplant‑Neo" for the complex treatment of gastrointestinal infections, investigation its antiexudative and spasmolytic activities.
Objects of the Study: Nifuroxazide, Plantaglucidum, Calendula extract, encapsulation mass and Diaplant‑Neocapsules.
Subject of Study: Development of the composition and technology of the combined drug in the form of capsules for the treatment of gastrointestinal infections.
Methods of the Study: Model of acute aseptic carrageenan inflammation, J. Setnicar method.
Results: Technological scheme of the Diaplant-Neo production was developed. As a result of a study of Diaplant-Neo, it was found that antiexudative activity is not significantly inferior to the effect of sodium diclofenac, antispasmodic activity corresponds to the action of plantaglucid.
Conclusion: The Diaplant‑Neocapsuleshas broad pharmacological properties, comprehensively affects acute intestinal infections pharmacotherapy, reduces the phenomenon of polypharmacy.
Keywords:
- Gastrointestinal infections
- technological flowchart
- Diaplant-Neo
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